Reese Witherspoon is set to delve into the drugs world by appearing in a comedy called Pharm Girl.

The 33-year-old actress has signed on to appear in the film about an upwardly mobile career girl in the pharmaceutical industry.

Witherspoon will not just act in the movie, she also plans to produce it through her production company Type A.

The mum-of-two recently lent her voice to the hit animated film Monsters vs. Aliens.